Nausea, emesis and anorexia

This public event is being presented as part of the conference 'Gut-brain communication in metabolic control and the regulation of energy homeostasis' (28.08. - 02.09.2022) and is being organised in cooperation with the Congressi Stefano Franscini/ETH Zürich.

Nausea, emesis and anorexia are among the most frequent symptoms of a myriad of diseases and drug treatments. These symptoms have serious negative effects on nutritional balance, quality of life and prognosis. A classic example are the nausea, vomiting and anorexia that occur following chemotherapy, despite the use of anti-emetic drugs.

Dr. Tito Borner's research, conducted in preclinical models, focuses on the neuronal centres in the brainstem that regulate nausea, emesis and anorexia and aims to develop new antiemetic therapies in order to improve patients' living conditions.

In this seminar he will explore the topic of nausea and vomiting from both an evolutionary and a neurobiological point of view, retrace some of the historical steps that led to the development of the major classes of antiemetics used in the field of oncology, and discuss what new therapies are currently being developed.

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